Monday, December 1, 2014

Genetic Patents: Who Owns the Genetic Material in Your Body?


Congratulations. For the time being, you are not owned by anyone. Are you surprised that you were before? If so, you aren’t the only one. You may be horrified to find out that until the recent Supreme Court decision of ACLU v. Myriad Genetics, a whopping 20 percent of the genetic material that is inside each one of our cells was patented by a host of pharmaceutical companies, labs, and individuals.

                All of this started in the 1980’s with the birth of DNA sequencing, bioengineering, and genetic manipulation. Until then, humans had found it difficult to manipulate or record the exact order and placement of the nucleotides that make up every organisms genetic material. As this became possible due to, at the time, earthshattering advances in science, companies began to seek ownership of this information and rights to all research concerning it. At that point, as is often the case with new technology, people did not grasp the gravity of the discovery or clearly see its potential for the future. The Supreme Court case Diamond v. Chakrabarty, came along and the justices ruled that though full and exclusive ownership of a natural gene was illegal, ownership of all processes concerning a natural gene in addition to any “man-made” gene was legal. With the relatively small amount of genes that were sequenced, not to mention lack of practical uses for them once they were isolated, the issue simply melted away.

                This all changed in the next 30 years. During this time, the human genome project had been begun and completed and scientist now knew how to manipulate, isolate, and find the function of most any gene in humans or other organisms. What had started as a slow trickle of patents concerning genetics had erupted into a deluge of patents all vying for the right to exclusively study a section of DNA. Not only was it animal and plant genes that were on the table, but human ones. There is great promise in companies that isolate and study these genes. For instance, a gene that contributes to a person developing diabetes may be able to be silenced if researched enough. However, most people disagree with this, arguing that exclusive rights to a gene bar all other institutions from researching as well. This is in addition to arguments against ownership to a part of the human, saying it makes no more ethical sense than being able to patent an organ like the heart or lungs.

                The Supreme Court upheld this sentiment recently in the case ACLU v. Myriad Genetics. The company Myriad Genetics had applied for a patent of two genes linked to breast cancer. This would give them exclusive rights to research and develop anything having to do with these genetic markers. Of course, this is mainly for financial gain. They had recently discovered that through testing with these genes, an extraordinarily accurate gene tests could predict the likelihood that a person would develop breast cancer. This meant that they could inflate prices of the test and make significantly more money. Though it sounds cutthroat, it is standard practice in business to do this to defend discoveries. The difference, the justices said, was that these were unaltered genes being copyrighted, not a process concerning them. They argued that they were made naturally meaning that they were no ones to exclusively own. With this, the copyrights of many companies were deemed void, opening research opportunities to anyone involved.
                This brings us to the next issue. Pharmaceutical companies can patent a lot that has to do with a gene. They can patent a method of finding the gene, isolating it, silencing it, or activating it. In addition, any change to a gene accomplished through any method makes that gene “man-made” and therefor eligible for a patent. This area of law is still relatively new and the boundaries have yet to be established. Depending on the direction the collective argument goes, we could one day live in a world in which certain genes found in peoples bodies naturally, but were “made” generations ago, are the intellectual property of a company. Are you scared yet? Excited? Only time will tell which side of the argument is right. Either way, this quiet court decision will go down as one of the most important in medical or scientific history.


For more information on this issue (or a better explanation that I have given), visit the link below and listen to the NPR discussion of the topic. There is also an embedded video outlining the basics of the subject.

http://www.npr.org/templates/story/story.php?storyId=125361332


 









Sources:


http://www.dailytech.com/Federal+Court+Rules+it+is+Illegal+to+Patent+Unaltered+Human+Genes/article18033.htm

http://www.extremetech.com/extreme/151686-do-you-own-your-own-genes-or-can-big-pharma-patent-them

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